Brighton and Hove Albion's Tomer Hemed grabbed the only goal as they ended Newcastle United's three-match winning streak with a 1-0 victory on Sunday in a battle between two of this season's promoted sides.
Norwich City and Newcastle United have been charged by the Football Association following a scuffle between Bradley Johnson and Loic Remy during a Premier League match last week.
Newcastle United completed the signing of Ajax Amsterdam midfielder Vurnon Anita on Thursday with the Dutch international hopeful his new club can end their 43-year trophyless spell.
IMAGES from the English Premier League matches played on Wednesday
Bernardo Silva and Jack Grealish scored three minutes apart as Manchester City came from behind to beat Premier League newcomers Luton Town.
Wolverhampton Wanderers stunned Tottenham Hotspur 2-1 with stoppage-time goals from Pablo Sarabia and Mario Lemina on Saturday, thwarting the visitors in their bid to reclaim top spot in the Premier League table.
Bukayo Saka scored either side of halftime as Arsenal crushed second-bottom Burnley 5-0.
Manager Graeme Souness' dismissal comes following the club's poor run of form this season.
A makeshift United defence that included Casemiro at centre-back was easily picked apart by Palace on several occasions
Nigeria striker Obafemi Martins left Inter Milan for Newcastle United for a fee of 15 million euros.
Watford have confirmed that three people from the club, including one player, have tested positive for COVID-19, while Burnley said their assistant coach Ian Woan was among those to return a positive result after being tested on Sunday.
Third-placed Aston Villa are the surprise package of the season and Unai Emery's side face relegation-threatened Burnley while fifth-placed Spurs host a resurgent Bournemouth who have 19 points from their last seven games.
Newcastle United named Alan Pardew as their 12th manager in the last 13 years on Thursday in place of Chris Hughton who was controversially sacked this week.
Despite playmaker James Maddison missing out due to an ankle injury, Leicester still got off to a great start when defender Pereira finished a surging run at the flat-footed Newcastle defence by slotting the ball home in the 16th minute.
Manchester City gave renewed hope to the chasing pack in the battle for a Champions League spot as they were held to a battling 1-1 draw at relegation strugglers Newcastle United on Tuesday.
Juergen Klopp's side remain seventh, six points behind the Champions League places, after only their second defeat in the 12 games since the German took over in October
Craig Bellamy scored twice in a 5-0 win in the UEFA Cup first round match.
"Our first half was fantastic, we dominated the game. The second is not easy to explain," a baffled Pochettino told reporters. "No-one would expect this end to the game if you see the first half. "We need to assess and analyse the second half because it is impossible to see the team playing in such a different way."
Newcastle United's Dutchman Giorginio Wijnaldum scored four times as they won their first Premier League match this season at the ninth attempt by thrashing Norwich City 6-2 to climb off the bottom of the table on Sunday.
Jarrod Bowen and Mohammed Kudus' second-half goals gave West Ham a 2-0 win over Manchester United in the Premier League's early game on Saturday, as the Hammers briefly moved into the top six.
Fulham striker Hugo Rodallega headed the decisive goal to seal a 2-1 win over Newcastle United in an absorbing Premier League match at Craven Cottage on Monday.
Rafa Benitez's much-changed side with a youthful streak had looked set to coast through when Sean Longstaff's deflected shot put them ahead after 56 seconds and Callum Roberts volleyed home a second four years since his only other Newcastle appearance.
Van Dijk was sent off for fouling Alexander Isak during the first half and appeared to remonstrate with referee John Brooks before walking off the pitch.
Newcastle United thrashed Queens Park Rangers 6-0 away to move into second place in the Championship (second tier) on Tuesday with former Liverpool midfielder Jonjo Shelvey scoring twice.
Everton's Theo Walcott struck just after halftime to secure a 1-0 home win over Newcastle United, on Monday, that took the Merseysiders up to eighth in the Premier League, their highest position this season.
Newcastle United finally put manager Steve McClaren out of his misery when they sacked him on Friday after a period of intense speculation surrounding his future.
Britain's Mo Farah capped his illustrious competitive racing career with a fourth-place finish at the Great North Run half-marathon in Newcastle on Sunday.
Newcastle United said Kevin Keegan was still their manager after a day of speculation that he had been sacked after just eight months in the job.
Antoine Griezmann and Samuel Lino scored in each half to give Atletico Madrid a 2-0 win over Lazio on Wednesday that secured them top spot in Champions League Group E, the first time since 2016 that they had reached the knockouts as group winners.
Newcastle United eased their relegation fears with a 2-0 home win over Fulham on Saturday as attention focused on the battle to stay in the Premier League.
Newcastle United drew a scrappy Premier League relegation clash 1-1 at Birmingham City on Monday leaving coach Kevin Keegan still without a win in eight league matches since returning to the club. The draw lifted Newcastle one spot to 14th with 29 points from 30 matches, while Birmingham rose from 17th to 16th taking their tally to 27 points from 30 games.
Manchester United were humbled 3-0 at home by Newcastle United in the League Cup fourth round
Sunderland are still not safe after losing 2-0 at Newcastle United in the day's second derby, Michael Owen scoring twice for Kevin Keegan's resurgent side at St James' Park.
Burnley beat Blackburn Rovers 2-0 at Ewood Park in their East Lancashire derby but Premier League sides Southampton and Newcastle United crashed out of the English League Cup to Championship opposition in Wednesday's second-round games.
Newcastle United maintained their unbeaten start to the season Saturday, sending Wigan Athletic to the bottom of the Premier League with a 1-0 victory at St James' Park thanks to a late winner from Frenchman Yohan Cabaye.
IMAGES from the Champions League matches played on Tuesday.
Premier League clubs have been in discussions to finish the season, which has nine rounds remaining, and the possibility of a restart next month was given a boost when the government said elite sport could return after June 1.
The 51-year-old resigned from Blackburn Rovers where he had been in charge since 2000.